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Real-World Effectiveness of High-Dose Tafamidis on Neurologic Disease Progression in Mixed-Phenotype Transthyretin Amyloid Cardiomyopathy

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NCT06393465

Sponsored by Pfizer (industry) · PFE — their whole pipeline →.

Phase
Status
Completed
Study type
Observational
Enrollment
50actual
Sites
1
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-06-15actualWhen the study began enrolling
Primary completion2026-04-07actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-04-07actualThe whole study's end, after follow-up
First posted2024-05-01actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-04-29actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

Intervention

  • Drug: Tafamidis — also filed as Vyndamax

Primary outcome

what the primary-completion date above is the date OF
Rate of neurologic disease progression
measured Baseline through at least 12 months of treatment

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