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First In Human Study of CX-2051 in Advanced Solid Tumors

← catalyst calendar

NCT06265688 · readout in 467 d

Sponsored by CytomX Therapeutics (industry) · CTMX — their whole pipeline →.

Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
160estimated
Sites
8
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-04-02actualWhen the study began enrolling
Primary completion2027-11-30estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2029-03-31estimatedThe whole study's end, after follow-up
First posted2024-02-20actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-07-15actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Solid Tumor, Adult

Interventions

  • Drug: CX-2051
  • Drug: Bevacizumab — also filed as Avastin

Primary outcomes

what the primary-completion date above is the date OF
Safety and tolerability of CX-2051
measured 44 months
Determine the recommended Phase 2 dose (RP2D)
measured 44 months

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