A Clinical Study of KK2260 in Patients With Advanced or Metastatic Solid Tumors
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Sponsored by Kyowa Kirin Co., Ltd. (industry) · 4151.T — their whole pipeline →.
Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
189estimated
Sites
14
Country
Japan
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2023-11-01 | actual | When the study began enrolling |
| Primary completion | 2029-10-31 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2030-04-30 | estimated | The whole study's end, after follow-up |
| First posted | 2024-02-08 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-05-27 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Advanced or Metastatic Solid Tumors
Interventions
- Drug: KK2260
- Drug: KK2260
Primary outcomes
what the primary-completion date above is the date OFDose-limiting toxicity (Only in Part 1a)
measured During the first cycle (1 Cycle = 28 days)
Adverse Events
measured Through study completion, an average of 1 year
Changes in Laboratory Testing Values (Red blood cell count)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Hemoglobin concentration)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Hematocrit)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Reticulocyte)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Mean corpuscular volume)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Mean corpuscular hemoglobin)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Mean corpuscular hemoglobin concentration)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (White blood cell count)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Differential white blood cells (basophils, eosinophils, lymphocytes, monocytes, neutrophils))
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Platelet count)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Total protein)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Albumin)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Alkaline phosphatase)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Alanine aminotransferase/Aspartate aminotransferase)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Total bilirubin/Direct bilirubin)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Blood urea nitrogen)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Calcium/Corrected Calcium)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Chloride)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Potassium)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Sodium)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Magnesium)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Serum iron)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Ferritin)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Total iron binding capacity)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Unsaturated iron binding capacity)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Serum creatinine)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Creatinine clearance (Cockcroft-Gault formula))
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Lactate dehydrogenase)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Blood glucose)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Uric acid)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Lipase)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Amylase)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (C-reactive protein)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Gamma-glutamyl transpeptidase)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Triglycerides)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Cholesterol)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Creatine phosphokinase)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Coagulation test)
measured Every week through study completion, an average of 1 year
Changes in Laboratory Testing Values (Hepatitis B virus DNA, if needed)
measured Every 2 cycle through study completion, an average of 1 year (1 Cycle = 28 days)
Changes in Body temperature (degree Celsius)
measured Every week through study completion, an average of 1 year
Changes in Systolic and Diastolic Blood Pressure (mmHg)
measured Every week through study completion, an average of 1 year
Changes in SpO2 (%)
measured Every week through study completion, an average of 1 year
Changes in Electrocardiogram parameters (Heart rate, PR interval, QRS interval, QT interval, and QTc intervals)
measured Every week through study completion, an average of 1 year
Changes in Eastern Cooperative Oncology Group Performance Status (ECOG PS) (The score should be 0 to 4, and the lower is the better.)
measured Every week through study completion, an average of 1 year
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