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A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

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NCT06228326 · readout ≤ 193 d

Sponsored by Krystal Biotech, Inc. (industry) · KRYS — their whole pipeline →.

Phase
Phase 1/2
Status
Recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
250estimated
Sites
14
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-04-17actualWhen the study began enrolling
Primary completionFeb 2027estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionJul 2028estimatedThe whole study's end, after follow-up
First posted2024-01-29actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-10-24actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Lung Cancer, Non-small Cell
  • Lung Cancer Metastatic
  • Solid Tumor, Adult
  • Advanced Cancer
  • Lung Cancer (NSCLC)

Interventions

  • Biological: KB707
  • Drug: Pembrolizumab (KEYTRUDA®)
  • Drug: Chemotherapy
  • Drug: Docetaxel

Primary outcome

what the primary-completion date above is the date OF
To evaluate the safety and tolerability of inhaled KB707 based upon assessment of adverse events (AE)
measured up to 36 months

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