RePOSA-Revealing the Efficacy of IHL-42X Use in Patients With OSA
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Phase
Phase 2/3
Status
Completed
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
121actual
Sites
20
Country
United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2024-05-02 | actual | When the study began enrolling |
| Primary completion | 2025-05-20 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-07-27 | actual | The whole study's end, after follow-up |
| First posted | 2023-11-24 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-07-27 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Obstructive Sleep Apnea
Interventions
- Drug: IHL-42X Low Dose — also filed as Phase 2 Investigational Product - IHL-42X Low dose
- Drug: IHL-42X High Dose — also filed as Phase 2 Investigational Product - IHL-42X High dose
- Drug: Placebo — also filed as Phase 2 Placebo
- Drug: IHL-42X (Optimal Dose) — also filed as Phase 3 Investigational Product - IHL-42X
- Drug: Dronabinol — also filed as Phase 3 Comparator - Reference Listed Drug/Dronabinol
- Drug: Acetazolamide — also filed as Phase 3 Comparator - Reference Listed Drug/Acetazolamide
- Drug: Placebo — also filed as Phase 3 Placebo
Primary outcomes
what the primary-completion date above is the date OFChange in apnea-hypopnea index (AHI)
measured 4 weeks
Change in apnea-hypopnea index (AHI)
measured 52 weeks
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