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A Study to Test a Medicine (Fitusiran) for Preventing Bleeds in People With Severe Hemophilia Who Previously Received Preventive Treatment With Emicizumab

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NCT06145373 · readout in 648 d

Sponsored by Sanofi (industry) · SNY — their whole pipeline →.

Phase
Phase 4
Status
Recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
20estimated
Sites
2
Countries
Taiwan, United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-03-01actualWhen the study began enrolling
Primary completion2028-05-28estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2030-01-30estimatedThe whole study's end, after follow-up
First posted2023-11-24actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-06-02actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Hemophilia A

Interventions

  • Drug: Fitusiran (SAR439774) — also filed as SAR439774, Qfitlia®
  • Biological: Clotting factor concentrates (CFC) or bypassing agents (BPA)
  • Biological: Antithrombin concentrate (ATIIIC)
  • Biological: Emicizumab

Primary outcome

what the primary-completion date above is the date OF
Number of participants with Adverse events (AEs) during the fitusiran treatment
measured From Day 1 up to Month 4

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