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AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies.

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NCT06137144 · readout in 988 d

Sponsored by AstraZeneca (industry) · AZN — their whole pipeline →.

Phase
Phase 1/2
Status
Recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
161estimated
Sites
37
Countries
Australia, China, France +7

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-01-23actualWhen the study began enrolling
Primary completion2029-05-03estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2029-05-03estimatedThe whole study's end, after follow-up
First posted2023-11-18actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-06-24actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Lymphoma
  • Non-Hodgkin Lymphoma
  • Hodgkin Lymphoma
  • Peripheral T-cell Lymphoma (PTCL)
  • PTCL-NOS
  • ALCL
  • AITL

Interventions

  • Drug: AZD3470
  • Drug: Pembrolizumab — also filed as Keytruda

Primary outcomes

what the primary-completion date above is the date OF
Incidence and severity of adverse events (AEs) and serious adverse events (SAEs)
measured From Screening continuously until 28 days after the last dose of study medication.
Incidence of DLTs (Dose Escalation Cohorts only)
measured From first dose of AZD3470 to end of Cycle 1 (each cycle is 21 days).

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