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A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and Placebo

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NCT06131372

Sponsored by Novo Nordisk A/S (industry) · NVO — their whole pipeline →.

Phase
Phase 2
Status
Completed
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
626actual
Sites
128
Countries
Argentina, Brazil, Canada +10

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2024-04-01actualWhen the study began enrolling
Primary completion2025-09-24actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2025-11-06actualThe whole study's end, after follow-up
First posted2023-11-14actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-04-01actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Chronic Kidney Disease
  • Type 2 Diabetes
  • Obesity

Interventions

  • Drug: Cagrilintide
  • Drug: Semaglutide
  • Drug: Placebo

Primary outcome

what the primary-completion date above is the date OF
Change in urinary albumin-to-creatinine ratio (UACR)
measured From baseline (week 0) to end of treatment (week 26)

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