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Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solution

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NCT06120842

Sponsored by SpyGlass Pharma, Inc. (industry) · SGP — their whole pipeline →.

Phase
Phase 1/2
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
201actual
Sites
1
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2023-10-13actualWhen the study began enrolling
Primary completion2025-01-31actualThe date the last participant is measured for the primary outcome — the readout window
Study completionNov 2027estimatedThe whole study's end, after follow-up
First posted2023-11-07actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-08-22actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Cataract
  • Glaucoma
  • Ocular Hypertension

Interventions

  • Drug: Bimatoprost Implant System (High Dose)
  • Drug: Bimatoprost Implant System (Low Dose)
  • Drug: Timolol Maleate Ophthalmic Solution, 0.5%
  • Device: Commercially Available Aspheric Monofocal Non-Yellow Chromophore IOL
  • Device: SpyGlass IOL

Primary outcome

what the primary-completion date above is the date OF
Mean IOP Reduction from Baseline (mmHg)
measured Weeks 2 and 6, and Month 3

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