JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors
← catalyst calendarNCT06108050 · readout in 468 d
Sponsored by Jazz Pharmaceuticals (industry) · JAZZ — their whole pipeline →. With Merck Sharp & Dohme LLC.
Phase
Phase 1
Status
Recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
177estimated
Sites
10
Country
United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2023-11-07 | actual | When the study began enrolling |
| Primary completion | 2027-11-30 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2028-05-31 | estimated | The whole study's end, after follow-up |
| First posted | 2023-10-30 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2025-12-16 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Conditions
- Advanced Solid Tumor
- Metastatic Solid Tumor
Interventions
- Drug: JZP898
- Drug: Pembrolizumab
Primary outcomes
what the primary-completion date above is the date OFNumber of Participants with Dose Limiting Toxicities in Monotherapy and Combination Therapy
measured Up to 36 months
Incidence of TEAEs and SAEs in Monotherapy and Combination Therapy
measured Up to 36 months
Incidence of dose interruptions, discontinuation, and reductions due to TEAEs in Monotherapy and Combination Therapy
measured Up to 36 months
Objective Response Rate (ORR) As Assessed by the Investigator In Combination Therapy
measured Up to 36 months
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