Randomized, Double-blind Study of Efficacy and Safety of Bexotegrast (PLN-74809) for Idiopathic Pulmonary Fibrosis
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Phase
Phase 2
Status
Terminated
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
320actual
Sites
268
Countries
Argentina, Australia, Belgium +22
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Why the sponsor stopped it
DSMB recommendation
As filed on the registry record, in the sponsor's own words.
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2023-11-16 | actual | When the study began enrolling |
| Primary completion | 2025-04-04 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-04-04 | actual | The whole study's end, after follow-up |
| First posted | 2023-10-24 | actual | When this record first appeared on the registry |
| Results posted | 2026-08-05 | actual | When the sponsor posted results to the registry |
| Record updated | 2026-08-05 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Idiopathic Pulmonary Fibrosis
Interventions
- Drug: PLN-74809
- Drug: Placebo
Primary outcome
what the primary-completion date above is the date OFChange From Baseline in Forced Vital Capacity at Week 52
measured Baseline (Day 1) and Week 52
Posted documents
hosted by the registry — we link, never re-serveStudy Protocol: v2.22_EUposted 2024-06-05 · 3.0 MB · Prot_001.pdf
Study Protocol: v1.2posted 2024-06-04 · 2.5 MB · Prot_000.pdf
Statistical Analysis Planposted 2025-04-02 · 2.2 MB · SAP_002.pdf
Publications
- PMID 41807015 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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