A Study of LY3556050 in Adult Participants With Diabetic Peripheral Neuropathic Pain
← catalyst calendarSponsored by Eli Lilly and Company (industry) · LLY — their whole pipeline →.
Phase
Phase 2
Status
Completed
Study type
Interventional
Design
Randomized · Double · Treatment
Enrollment
404actual
Sites
70
Countries
Czechia, Japan, Poland +2
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2023-10-05 | actual | When the study began enrolling |
| Primary completion | 2025-06-11 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-06-11 | actual | The whole study's end, after follow-up |
| First posted | 2023-10-10 | actual | When this record first appeared on the registry |
| Results posted | 2026-07-30 | actual | When the sponsor posted results to the registry |
| Record updated | 2026-07-30 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Diabetic Peripheral Neuropathy
Interventions
- Drug: Mazisotine — also filed as LY3556050
- Drug: Placebo
Primary outcomes
what the primary-completion date above is the date OFMean Change From Baseline in Average Pain Intensity (API) as Measured by Weekly Average of Numeric Rating Scale (NRS) - Bayesian Model Averaging (BMA) Dose-response Model
measured Baseline, Week 12
Mean Change From Baseline in Average Pain Intensity (API) as Measured by Weekly Average of Numeric Rating Scale (NRS) - Frequentist Repeated Measures (FRM) Analysis
measured Baseline, Week 12
Posted documents
hosted by the registry — we link, never re-serveStudy Protocolposted 2024-05-14 · 4.4 MB · Prot_000.pdf
Statistical Analysis Planposted 2025-06-06 · 1.2 MB · SAP_001.pdf
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