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A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma

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NCT06054555 · readout in 523 d

Sponsored by Amgen (industry) · AMGN — their whole pipeline →.

Phase
Phase 3
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · Double · Treatment
Enrollment
633actual
Sites
180
Countries
Argentina, Bosnia and Herzegovina, Canada +28

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2023-11-02actualWhen the study began enrolling
Primary completion2028-01-25estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2028-01-25estimatedThe whole study's end, after follow-up
First posted2023-09-26actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-01-12actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Melanoma

Interventions

  • Drug: ABP 206
  • Drug: Nivolumab — also filed as OPDIVO®

Primary outcomes

what the primary-completion date above is the date OF
Objective response by Week 49
measured Week 49
Objective response at Week 17
measured Week 17
Progression-free survival (PFS)
measured From Randomization until Follow-up or End of treatment (EOT) or Early termination (ET) (Approximately 105 Weeks)
Overall survival (OS)
measured From Randomization until Follow-up or EOT or ET (Approximately 105 Weeks)
Duration of response (DOR)
measured From Randomization until Follow-up or EOT or ET (Approximately 105 Weeks)

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