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A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma

← catalyst calendar

NCT06023589 · readout in 651 d

Sponsored by AstraZeneca (industry) · AZN — their whole pipeline →. With Amgen.

Phase
Phase 3
Status
Recruiting
Study type
Interventional
Design
Randomized · Triple · Treatment
Enrollment
231estimated
Sites
147
Countries
Argentina, Brazil, Canada +19

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2023-08-24actualWhen the study began enrolling
Primary completion2028-05-31estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2030-08-23estimatedThe whole study's end, after follow-up
First posted2023-09-05actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-17actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Asthma

Interventions

  • Biological: Tezepelumab — also filed as MEDI9929 and AMG157
  • Other: Placebo

Primary outcome

what the primary-completion date above is the date OF
Annualized severe asthma exacerbation rate (AAER)
measured From Baseline to Week 52

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