A Relative Bioavailability and Food Effect Study of TYRA-300-B01 Capsule and Tablet Formulations in Healthy Adult Participants
← catalyst calendarSponsored by Tyra Biosciences, Inc (industry) · TYRA — their whole pipeline →.
Phase
Phase 1
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
60estimated
Sites
1
Country
Australia
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2023-10-16 | actual | When the study began enrolling |
| Primary completion | May 2025 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | Jul 2025 | estimated | The whole study's end, after follow-up |
| First posted | 2023-08-23 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2025-03-26 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Healthy
Intervention
- Drug: TYRA-300-B01
Primary outcomes
what the primary-completion date above is the date OFPharmacokinetics single-dose Cmax
measured Up to 48 hours post-dose
Pharmacokinetics multiple-dose Cmax
measured Up to 24 hours post-dose
Pharmacokinetics multiple-dose Cmin
measured Up to 24 hours post-dose
Pharmacokinetics single dose Tmax
measured Up to 48 hours post-dose
Pharmacokinetics single and multiple dose AUC
measured Up to 48 hours post-dose
Pharmacokinetics single dose CL/F
measured Up to 48 hours post-dose
Pharmacokinetics single dose Vz/F
measured Up to 48 hours post-dose
Pharmacokinetics single dose t1/2
measured Up to 48 hours post-dose
Pharmacokinetics multiple-dose RCmax
measured Up to 24 hours post-dose
Pharmacokinetics multiple-dose RAUC
measured Up to 24 hours post-dose
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