A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee
← catalyst calendarSponsored by Organogenesis (industry) · ORGO — their whole pipeline →.
Phase
Phase 3
Status
Completed
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
594actual
Sites
41
Country
United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2023-09-06 | actual | When the study began enrolling |
| Primary completion | 2025-08-15 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-11-30 | actual | The whole study's end, after follow-up |
| First posted | 2023-08-21 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-04-21 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Knee Osteoarthritis
Interventions
- Biological: Amniotic Suspension Allograft
- Drug: Placebo
Primary outcome
what the primary-completion date above is the date OFThe difference in change from baseline in WOMAC Pain scale at 6 months between ASA- and placebo-treated patients
measured Baseline to Week 26
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