A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
← catalyst calendarNCT05986292 · readout ≤ 254 d
Sponsored by Eli Lilly and Company (industry) · LLY — their whole pipeline →.
Phase
Phase 2
Status
Recruiting
Study type
Interventional
Design
Randomized · Double · Screening
Enrollment
10,000estimated
Sites
64
Countries
Puerto Rico, United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2020-01-30 | actual | When the study began enrolling |
| Primary completion | Apr 2027 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | Apr 2027 | estimated | The whole study's end, after follow-up |
| First posted | 2023-08-14 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-06-23 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Conditions
- Osteoarthritis, Knee
- Diabetic Neuropathic Pain
- Chronic Low-back Pain
Interventions
- Drug: LY3016859 ISA
- Drug: LY3556050 ISA
- Drug: LY3526318 ISA
- Drug: LY3857210 ISA
- Drug: Placebo Oral
- Drug: Placebo
Primary outcome
what the primary-completion date above is the date OFNumber of Participants Who Were Allocated to Each ISA
measured Baseline, Up to Week 8
Posted documents
hosted by the registry — we link, never re-serveStudy Protocolposted 2020-12-11 · 6.0 MB · Prot_005.pdf
Publications
- PMID 39430683 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
Permalink · LLY's whole pipeline · Catalyst calendar · Every registered study · What changed