Cough Reduction in IPF With Nalbuphine ER
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Phase
Phase 2
Status
Completed
Study type
Interventional
Design
Randomized · Double · Treatment
Enrollment
165actual
Sites
59
Countries
Australia, Canada, Chile +7
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2024-02-06 | actual | When the study began enrolling |
| Primary completion | 2025-04-24 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-04-24 | actual | The whole study's end, after follow-up |
| First posted | 2023-07-27 | actual | When this record first appeared on the registry |
| Results posted | 2026-06-26 | actual | When the sponsor posted results to the registry |
| Record updated | 2026-06-26 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Idiopathic Pulmonary Fibrosis
Interventions
- Drug: NAL ER — also filed as Nalbuphine
- Drug: Placebo
- Drug: NAL ER — also filed as Nalbuphine
- Drug: NAL ER — also filed as Nalbuphine
Primary outcome
what the primary-completion date above is the date OFRelative Change From Baseline in 24-hour Cough Frequency at Week 6
measured Baseline, Week 6
Posted documents
hosted by the registry — we link, never re-serveStudy Protocolposted 2024-05-20 · 8.4 MB · Prot_000.pdf
Statistical Analysis Planposted 2025-05-20 · 4.8 MB · SAP_001.pdf
Publications
- PMID 41569557 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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