A Study of Once-Daily Oral Orforglipron (LY3502970) in Japanese Adult Participants With Obesity Disease
← catalyst calendarSponsored by Eli Lilly and Company (industry) · LLY — their whole pipeline →.
Phase
Phase 3
Status
Completed
Study type
Interventional
Design
Randomized · Double · Treatment
Enrollment
238actual
Sites
16
Country
Japan
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2023-07-31 | actual | When the study began enrolling |
| Primary completion | 2025-06-19 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-06-19 | actual | The whole study's end, after follow-up |
| First posted | 2023-07-05 | actual | When this record first appeared on the registry |
| Results posted | 2026-07-20 | actual | When the sponsor posted results to the registry |
| Record updated | 2026-07-20 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Obesity
Interventions
- Drug: Orforglipron
- Drug: Placebo
Primary outcomes
what the primary-completion date above is the date OFPercent Change From Baseline in Body Weight at Week 72
measured Baseline, Week 72
Percentage of Participants Who Achieved With Greater Than or Equal to (≥) 5% Body Weight Reduction From Baseline
measured Baseline to Week 72
Posted documents
hosted by the registry — we link, never re-serveStudy Protocol: Amendment (b)posted 2023-12-07 · 1.7 MB · Prot_000.pdf
Study Protocol: Errata to Amendment (b)posted 2024-01-11 · 179 KB · Prot_001.pdf
Statistical Analysis Planposted 2025-08-05 · 994 KB · SAP_002.pdf
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