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A Study to Evaluate Impact of Efanesoctocog Alfa on Long-term Joint Health in Participants With Hemophilia A

← catalyst calendar

NCT05911763 · readout in 657 d

Sponsored by Sanofi (industry) · SNY — their whole pipeline →.

Phase
Status
Active, not recruiting
Study type
Observational
Enrollment
200estimated
Sites
28
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2023-06-30actualWhen the study began enrolling
Primary completion2028-06-06estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2030-09-17estimatedThe whole study's end, after follow-up
First posted2023-06-22actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-10-02actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Hemophilia A

Intervention

  • Drug: Efanesoctocog Alfa BIVV001 — also filed as ALTUVIIIO

Primary outcomes

what the primary-completion date above is the date OF
Change from baseline in Annualized joint bleeding rate (AjBR) for treated bleeds
measured Up to 5 years
Change from baseline in Annualized joint bleeding rate (AjBR) for all (treated and untreated) bleeds
measured Up to 5 years
Number of Target joint development, resolution and/or recurrence
measured Up to 5 years

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