A Study to Investigate the Effect of XYWAV on Sleepiness, Polysomnography, and Functional Outcomes in Participants With Idiopathic Hypersomnia or Narcolepsy
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Phase
Phase 4
Status
Completed
Study type
Interventional
Design
Na · None · Treatment
Enrollment
207actual
Sites
32
Countries
Canada, United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2023-07-27 | actual | When the study began enrolling |
| Primary completion | 2025-03-13 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-03-13 | actual | The whole study's end, after follow-up |
| First posted | 2023-05-25 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2025-07-17 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Conditions
- Idiopathic Hypersomnia
- Narcolepsy
Intervention
- Drug: JZP258 (XYWAV)
Primary outcome
what the primary-completion date above is the date OFEpworth Sleepiness Scale (ESS) Total Score in Participants With IH and Narcolepsy Treated With XYWAV
measured Baseline up to End of Treatment (approximately 10-36 weeks)
Publications
- PMID 42060037 — linked by the registry
- PMID 41831073 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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