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Avalglucosidase Alfa Pregnancy Study

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NCT05734521 · readout in 2,265 d

Sponsored by Sanofi (industry) · SNY — their whole pipeline →.

Phase
Status
Recruiting
Study type
Observational
Enrollment
100estimated
Sites
1
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2022-10-26actualWhen the study began enrolling
Primary completion2032-10-31estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2032-10-31estimatedThe whole study's end, after follow-up
First posted2023-02-21actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-01-16actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Pompe Disease
  • Pregnancy

Interventions

  • Biological: avalglucosidase alfa-NGPT (GZ402666) IV — also filed as NEXVIAZYME
  • Biological: avalglucosidase alfa-NGPT (GZ402666) — also filed as NEXVIAZYME

Primary outcomes

what the primary-completion date above is the date OF
Maternal complications
measured through study completion, an average of 10 years
Pregnancy outcome
measured through study completion, an average of 10 years
Infant outcome
measured through study completion, an average of 10 years

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