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A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab))

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NCT05731128

Sponsored by Sanofi (industry) · SNY — their whole pipeline →. With Regeneron Pharmaceuticals.

Phase
Phase 2
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
68actual
Sites
77
Countries
Argentina, Canada, Chile +8

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2023-01-12actualWhen the study began enrolling
Primary completion2026-05-13actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2027-02-22estimatedThe whole study's end, after follow-up
First posted2023-02-16actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-06-23actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Colitis Ulcerative

Interventions

  • Drug: Dupilumab — also filed as Dupixent
  • Drug: Placebo

Primary outcome

what the primary-completion date above is the date OF
Proportion of participants achieving clinical response at Week 24
measured Week 24

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