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A Study of ELI-002 7P in Subjects With KRAS/NRAS Mutated Solid Tumors

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NCT05726864

Sponsored by Elicio Therapeutics (industry) · ELTX — their whole pipeline →.

Phase
Phase 1/2
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
158actual
Sites
28
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2023-04-14actualWhen the study began enrolling
Primary completion2026-04-20actualThe date the last participant is measured for the primary outcome — the readout window
Study completionNov 2026estimatedThe whole study's end, after follow-up
First posted2023-02-14actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-07-10actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Pancreatic Ductal Adenocarcinoma
  • Colorectal Cancer
  • KRAS G12D
  • KRAS G12R
  • KRAS G12V
  • KRAS G12A
  • KRAS G12C
  • KRAS G12S
  • KRAS G13D
  • NRAS G12D
  • NRAS G12R
  • NRAS G12V
  • NRAS G12C
  • NRAS G12S

Intervention

  • Drug: ELI-002 7P

Primary outcomes

what the primary-completion date above is the date OF
Phase 1: Evaluate the safety of ELI-002 7P
measured 28 days after the first dose of ELI-002 7P
Phase 2: Compare ELI-002 7P versus standard of care (SOC; observation) in DFS (disease free survival)
measured After the last radiographic assessment at Visit 26 (Week 150)

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