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Study With Various Immunotherapy Treatments in Participants With Lung Cancer

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NCT05676931 · readout ≤ 499 d

Sponsored by Gilead Sciences (industry) · GILD — their whole pipeline →. With Arcus Biosciences, Inc..

Phase
Phase 2
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
400estimated
Sites
53
Countries
Australia, France, Georgia +7

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2023-02-21actualWhen the study began enrolling
Primary completionDec 2027estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionDec 2027estimatedThe whole study's end, after follow-up
First posted2023-01-09actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-06-01actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Advanced Non-Small Cell Lung Cancer

Interventions

  • Drug: Domvanalimab
  • Drug: Quemliclustat
  • Drug: Zimberelimab
  • Drug: Docetaxel
  • Drug: Platinum-Based Doublet

Primary outcomes

what the primary-completion date above is the date OF
Objective response rate (ORR) as measured by Response Evaluation Criteria in Solid Tumors (RECIST v1.1)
measured Up to 58 months
The incidence and severity of adverse events (AEs) and serious adverse events (SAEs)
measured Up to 58 months

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