Does Screening With the Galleri Test in the NHS Reduce the Likelihood of a Late-stage Cancer Diagnosis in an Asymptomatic Population? A Randomised Clinical Trial
← catalyst calendarSponsored by GRAIL, Inc. (industry) · GRAL — their whole pipeline →. With The Cancer Research UK Cancer Prevention Trials Unit at Queen Mary University of London (CPTU).
Phase
Not applicable
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · Triple · Screening
Enrollment
142,318actual
Sites
1
Country
United Kingdom
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2021-08-31 | actual | When the study began enrolling |
| Primary completion | 2026-06-12 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | Jan 2031 | estimated | The whole study's end, after follow-up |
| First posted | 2022-11-10 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-07-10 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Cancer
Intervention
- Device: Multi-cancer early detection test (Galleri test) — also filed as Galleri test
Primary outcome
what the primary-completion date above is the date OFincidence of stage III and IV cancers diagnosed in the intervention arm as compared with the control arm
measured 3-4 years after randomization
Publications
- PMID 37479515 — cited as background
- PMID 36230741 — cited as background
- PMID 37095697 — cited as background
- PMID 41567711 — linked by the registry
- PMID 39862108 — linked by the registry
- PMID 38429085 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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