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Atacicept in Subjects With Active Lupus Nephritis (COMPASS)

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NCT05609812

Sponsored by Vera Therapeutics, Inc. (industry) · VERA — their whole pipeline →.

Phase
Phase 3
Status
Withdrawn
Study type
Interventional
Design
Randomized · Double · Treatment
Enrollment
0actual
Sites
33
Countries
Puerto Rico, Spain, United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Why the sponsor stopped it

Study recruitment is paused due to business reasons, but not due to regulatory or safety concerns.

As filed on the registry record, in the sponsor's own words.

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2022-11-02actualWhen the study began enrolling
Primary completion2026-03-15estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2028-12-15estimatedThe whole study's end, after follow-up
First posted2022-11-08actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-05-23actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Lupus Nephritis (LN)

Interventions

  • Drug: Atacicept — also filed as VT-001
  • Drug: Placebo

Primary outcome

what the primary-completion date above is the date OF
Renal Response as definedas UPCR ≤0.5 mg/mg, and eGFR ≥60 mL/min/1.73 m^2 or eGFR <60 mL/min/1.73 m^2 with no confirmed decrease from baseline of >20%
measured Week 52

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