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A Global, Multicenter Study to Assess Maternal, Fetal and Infant Outcomes of Exposure to Palynziq® (Pegvaliase) During Pregnancy and Breastfeeding

← catalyst calendar

NCT05579548 · readout in 2,238 d

Sponsored by BioMarin Pharmaceutical (industry) · BMRN — their whole pipeline →. With Syneos Health.

Phase
Status
Recruiting
Study type
Observational
Enrollment
50estimated
Sites
4
Countries
Canada, Germany, Italy +1

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2022-11-22actualWhen the study began enrolling
Primary completion2032-10-04estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2032-10-04estimatedThe whole study's end, after follow-up
First posted2022-10-14actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-03-24actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Phenylketonuria, Maternal

Intervention

  • Drug: Pegvaliase

Primary outcome

what the primary-completion date above is the date OF
Pregnancy outcome and infant development for women who have been treated with Palynziq (pegvaliase) within 2 weeks of their last menstrual period
measured 10 years

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