A Study of EDG-5506 in Children With Duchenne Muscular Dystrophy (LYNX)
← catalyst calendarNCT05540860 · readout ≤ 164 d
Sponsored by Edgewise Therapeutics, Inc. (industry) · EWTX — their whole pipeline →.
Phase
Phase 2
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
76actual
Sites
14
Country
United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2022-10-24 | actual | When the study began enrolling |
| Primary completion | Jan 2027 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | Jan 2027 | estimated | The whole study's end, after follow-up |
| First posted | 2022-09-15 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2025-11-12 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Duchenne Muscular Dystrophy
Interventions
- Drug: Sevasemten Dose 1
- Drug: Sevasemten Dose 2
- Drug: Sevasemten Dose 3
- Drug: Sevasemten Dose 4
- Drug: Sevasemten Dose 5
- Drug: Placebo
Primary outcomes
what the primary-completion date above is the date OFNumber of adverse events during treatment with sevasemten or placebo
measured 48 months
Severity of adverse events during treatment with sevasemten or placebo
measured 48 months
Permalink · EWTX's whole pipeline · Catalyst calendar · Every registered study · What changed