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Study of Fordadistrogene Movaparvovec in Early Stage Duchenne Muscular Dystrophy

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NCT05429372

Sponsored by Pfizer (industry) · PFE — their whole pipeline →.

Phase
Phase 2
Status
Terminated
Study type
Interventional
Design
Na · None · Treatment
Enrollment
10actual
Sites
13
Countries
Australia, United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Why the sponsor stopped it

All participants who have received fordadistrogene movaparvovec in any Pfizer study will now be assessed for long-term safety in one combined study: C3391003

As filed on the registry record, in the sponsor's own words.

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2022-08-08actualWhen the study began enrolling
Primary completion2025-10-03actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2025-10-03actualThe whole study's end, after follow-up
First posted2022-06-23actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-10-21actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Muscular Dystrophy, Duchenne

Intervention

  • Genetic: PF-06939926 — also filed as Fordadistrogene Movaparvovec

Primary outcomes

what the primary-completion date above is the date OF
Incidence and severity of Treatment-Emergent Adverse Events and Serious Adverse Events
measured Through Week 52
Number of participants with abnormal hematology test results
measured Through Week 52
Number of participants with abnormal biochemistry test results
measured Through Week 52
Number of participants with abnormal urine analysis
measured Through Week 52
Number of participants with abnormal and clinically relevant changes in neurological examinations
measured Through Week 52
Number of participants with abnormal and clinically relevant changes in body weight
measured Through Week 52
Number of participants with abnormal and clinically relevant changes in vital signs
measured Through Week 52
Number of participants with abnormal and clinically relevant changes on cardiac troponin I
measured Through Week 52
Number of participants with abnormal and clinically relevant changes on electrocardiogram (ECG)
measured Through Week 52
Number of participants with abnormal and clinically relevant changes on echocardiogram
measured Through Week 52

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