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Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.

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NCT05401357

Sponsored by Amneal Pharmaceuticals, LLC (industry) · AMRX — their whole pipeline →. With CBCC Global Research.

Phase
Phase 3
Status
Recruiting
Study type
Interventional
Design
Randomized · Single · Treatment
Enrollment
168estimated
Sites
9
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2022-06-29actualWhen the study began enrolling
Primary completionDec 2022estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionDec 2022estimatedThe whole study's end, after follow-up
First posted2022-06-02actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2022-08-10actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Glaucoma, Open-Angle
  • Ocular Hypertension

Interventions

  • Drug: Test - Bimatoprost 0.01% Ophthalmic Solution
  • Drug: Reference - LUMIGAN® (Bimatoprost 0.01% Ophthalmic Solution)

Primary outcome

what the primary-completion date above is the date OF
Mean difference in the intraocular pressure (IOP) of both eyes between the two treatment groups.
measured Day 14 and 42 at 00.00 hours, 04.00 hours, and 08.00 hours.

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