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A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies

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NCT05362773 · readout ≤ 102 d

Sponsored by MacroGenics (industry) · MGNX — their whole pipeline →.

Phase
Phase 1
Status
Active, not recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
130estimated
Sites
7
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2022-07-13actualWhen the study began enrolling
Primary completionNov 2026estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionMay 2027estimatedThe whole study's end, after follow-up
First posted2022-05-05actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-07-28actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Leukemia, Acute Myeloid
  • Myelodysplastic Syndromes
  • Classical Hodgkin Lymphoma
  • Leukemia, B-cell
  • Leukemia, Hairy Cell
  • Mastocytosis, Aggressive Systemic
  • Blastic Plasmacytoid Dendritic Cell Neoplasm
  • Chronic Myeloid Leukemia

Intervention

  • Drug: MGD024

Primary outcomes

what the primary-completion date above is the date OF
Number of severe side effects in patients receiving MGD024
measured First 28 days of the study
Number and types of adverse events (AEs), including serious adverse events (SAEs), and AEs leading to treatment discontinuation.
measured Throughout study participation, up to 12 months.

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