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Efficacy of Romiplostim in Treatment of SAA in Adults Previously Untreated With or Refractory to Immunosuppressive Therapy

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NCT05323617

Sponsored by Amgen (industry) · AMGN — their whole pipeline →.

Phase
Phase 2
Status
Withdrawn
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
0actual

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Why the sponsor stopped it

Operational

As filed on the registry record, in the sponsor's own words.

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2023-08-31estimatedWhen the study began enrolling
Primary completion2025-02-25estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2025-02-25estimatedThe whole study's end, after follow-up
First posted2022-04-12actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2023-09-29actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Severe Aplastic Anemia (SAA)

Interventions

  • Drug: Romiplostim — also filed as Nplate®
  • Drug: Antithymocyte Globulin
  • Drug: Cyclosporine A

Primary outcome

what the primary-completion date above is the date OF
Arms 1 and 2: proportion of participants achieving any hematologic response at week 14
measured Week 14

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