The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials
← catalyst calendarNCT05203172 · readout in 1,077 d
Sponsored by Pfizer (industry) · PFE — their whole pipeline →.
Phase
Phase 4
Status
Recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
46estimated
Sites
67
Countries
Australia, Brazil, Canada +14
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2022-07-05 | actual | When the study began enrolling |
| Primary completion | 2029-07-31 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2029-07-31 | estimated | The whole study's end, after follow-up |
| First posted | 2022-01-24 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-04-07 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Solid Tumors
Interventions
- Drug: Binimetinib only treatment
- Drug: Encorafenib only Treatment
- Drug: Encorafenib & Binimetinib Treatment
- Drug: Treatment of Encorafenib & Binimetinib & Ribociclib
- Drug: Treatment of Encorafenib & Binimetinib & Cetuximab
Primary outcomes
what the primary-completion date above is the date OFNumber of participants with adverse events leading to permanent discontinuation of study intervention
measured Baseline up to approximately 5 years
Number serious adverse events reported for all participants
measured Baseline up to approximately 5 years
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