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A Study to Evaluate the Safety and Efficacy of EscharEx (EX-02) in the Treatment of Basal Cell Carcinoma

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NCT05157763

Sponsored by MediWound Ltd (industry) · MDWD — their whole pipeline →.

Phase
Phase 1/2
Status
Recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
32estimated
Sites
3
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2021-06-30actualWhen the study began enrolling
Primary completionMay 2022estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionJun 2022estimatedThe whole study's end, after follow-up
First posted2021-12-15actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2021-12-15actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Superficial Basal Cell Carcinoma
  • Nodular Basal Cell Carcinoma

Intervention

  • Drug: EscharEx 5% (EX-02 formulation) — also filed as EX-02 5%

Primary outcomes

what the primary-completion date above is the date OF
Incidence and severity of treatment-emergent AEs (TEAEs) and serious TEAEs (STEAEs).
measured Through study completion - an average of 16 weeks
Vital signs - proportion of patients with abnormal clinical significant measurements
measured Up to completion of treatment period - up to 5 weeks
Pain assessments- Proportion of patients with clinical significant elevation in NPRS score
measured Up to completion of treatment period - up to 5 weeks
Proportion of subjects discontinuing a treatment due to TEAEs, assessed over the entire course of the treatment.
measured Up to completion of treatment period - up to 5 weeks
Proportion of subjects that requested to discontinue the treatment
measured Up to completion of treatment period - up to 5 weeks

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