A Study of Lu AF82422 in Participants With Multiple System Atrophy
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Phase
Phase 2
Status
Active, not recruiting
Study type
Interventional
Design
Randomized · Triple · Treatment
Enrollment
64actual
Sites
19
Countries
Japan, United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2021-11-16 | actual | When the study began enrolling |
| Primary completion | 2023-11-16 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2028-03-07 | estimated | The whole study's end, after follow-up |
| First posted | 2021-11-03 | actual | When this record first appeared on the registry |
| Results posted | 2024-12-27 | actual | When the sponsor posted results to the registry |
| Record updated | 2026-04-13 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Multiple System Atrophy
Interventions
- Drug: Lu AF82422
- Drug: Placebo
Primary outcome
what the primary-completion date above is the date OFPercentage Slowing of Clinical Progression Based on Change From Baseline in the UMSARS TS at the End of Treatment (EOT) DB Period (DBP)
measured Baseline up to Week 72
Posted documents
hosted by the registry — we link, never re-serveStudy Protocolposted 2024-05-29 · 4.1 MB · Prot_000.pdf
Statistical Analysis Planposted 2023-12-20 · 2.5 MB · SAP_001.pdf
Publications
- PMID 42044642 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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