Study of ARO-C3 in Adult Healthy Volunteers and Patients With Complement Mediated Renal Disease
← catalyst calendarSponsored by Arrowhead Pharmaceuticals (industry) · ARWR — their whole pipeline →.
Phase
Phase 1/2
Status
Completed
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
62actual
Sites
16
Countries
Australia, Georgia, Germany +4
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2022-02-01 | actual | When the study began enrolling |
| Primary completion | 2025-09-10 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-09-10 | actual | The whole study's end, after follow-up |
| First posted | 2021-10-19 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-05-22 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Conditions
- C3 Glomerulopathy
- IgA Nephropathy
Interventions
- Drug: ARO-C3
- Drug: Placebo
Primary outcome
what the primary-completion date above is the date OFNumber of Participants with Adverse Events (AEs) and/or Serious Adverse Events (SAEs) at Day 169
measured up to day 169 (End of Study [EOS])
Publications
- PMID 38299639 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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