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Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program

← catalyst calendar

NCT05040373 · readout in 1,515 d

Sponsored by Alnylam Pharmaceuticals (industry) · ALNY — their whole pipeline →.

Phase
Status
Recruiting
Study type
Observational
Enrollment
10estimated
Sites
7
Countries
France, Germany, Italy +4

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2020-08-01actualWhen the study began enrolling
Primary completion2030-10-12estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2030-10-12estimatedThe whole study's end, after follow-up
First posted2021-09-10actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-06-01actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Hereditary Transthyretin-mediated (hATTR) Amyloidosis
  • Polyneuropathy

Primary outcome

what the primary-completion date above is the date OF
Prevalence of Major Congenital Malformations
measured From 12 weeks prior to last dose of patisiran through one year after birth (Up to 21 months)

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