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MANDARIN (S6371)

← catalyst calendar

NCT05016245

Sponsored by Boston Scientific Corporation (industry) · BSX — their whole pipeline →.

Phase
Phase 3
Status
Completed
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
92actual
Sites
1
Country
China

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2021-09-13actualWhen the study began enrolling
Primary completion2026-02-13actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-08-10actualThe whole study's end, after follow-up
First posted2021-08-23actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-08-12actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Inoperable Hepatocellular Carcinoma

Interventions

  • Combination product: TheraSphere™ Yttrium-90 Glass Microspheres
  • Procedure: conventional Transarterial Chemoembolization(cTACE)

Primary outcomes

what the primary-completion date above is the date OF
Time to progression (TTP)
measured through study completion, an average of 18 months
Safety assessed within 60 days post treatment using NCI-CTCAE v5.0
measured within 60 days post treatment

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