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XmAb®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer

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NCT05005728

Sponsored by Xencor, Inc. (industry) · XNCR — their whole pipeline →.

Phase
Phase 2
Status
Completed
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
72actual
Sites
26
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2021-10-22actualWhen the study began enrolling
Primary completion2025-06-10actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2025-06-10actualThe whole study's end, after follow-up
First posted2021-08-13actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-05-05actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Metastatic Castration-Resistant Prostate Cancer

Interventions

  • Combination product: vudalimab + carboplatin + cabazitaxel
  • Combination product: vudalimab + olaparib
  • Biological: vudalimab monotherapy
  • Combination product: vudalimab + docetaxel
  • Combination product: vudalimab + cabazitaxel or docetaxel

Primary outcome

what the primary-completion date above is the date OF
Incidence of treatment-emergent adverse events (safety and tolerability of vudalimab)
measured 8 weeks

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