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A Study of Subcutaneous (SC) AMG 701 in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

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NCT04998747

Sponsored by Amgen (industry) · AMGN — their whole pipeline →.

Phase
Phase 1
Status
Withdrawn
Study type
Interventional
Design
Non randomized · None · Basic science
Enrollment
0actual

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Why the sponsor stopped it

Amgen Decision to stop development of AMG 701 SC, not for safety reasons but for business reasons.

As filed on the registry record, in the sponsor's own words.

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2023-08-29estimatedWhen the study began enrolling
Primary completion2025-08-02estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completion2025-08-28estimatedThe whole study's end, after follow-up
First posted2021-08-10actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2022-09-27actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Relapsed/Refractory Multiple Myeloma

Interventions

  • Drug: AMG 701
  • Drug: AMG 701

Primary outcomes

what the primary-completion date above is the date OF
Number of participants who experience dose-limiting toxicities (DLTs)
measured 28 days
Number of participants who experience one or more treatment-emergent adverse events (TEAEs)
measured up to approximately 9 months
Number of participants who experience one or more treatment-related TEAEs
measured up to approximately 9 months
Number of participants with abnormal changes in vital signs
measured up to approximately 9 months
Number of participants with abnormal changes in electrocardiograms (ECGs) findings
measured up to approximately 9 months
Number of participants with abnormal changes in clinical laboratory tests
measured up to approximately 9 months

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