A Study of Subcutaneous (SC) AMG 701 in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
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Phase
Phase 1
Status
Withdrawn
Study type
Interventional
Design
Non randomized · None · Basic science
Enrollment
0actual
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Why the sponsor stopped it
Amgen Decision to stop development of AMG 701 SC, not for safety reasons but for business reasons.
As filed on the registry record, in the sponsor's own words.
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2023-08-29 | estimated | When the study began enrolling |
| Primary completion | 2025-08-02 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-08-28 | estimated | The whole study's end, after follow-up |
| First posted | 2021-08-10 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2022-09-27 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Relapsed/Refractory Multiple Myeloma
Interventions
- Drug: AMG 701
- Drug: AMG 701
Primary outcomes
what the primary-completion date above is the date OFNumber of participants who experience dose-limiting toxicities (DLTs)
measured 28 days
Number of participants who experience one or more treatment-emergent adverse events (TEAEs)
measured up to approximately 9 months
Number of participants who experience one or more treatment-related TEAEs
measured up to approximately 9 months
Number of participants with abnormal changes in vital signs
measured up to approximately 9 months
Number of participants with abnormal changes in electrocardiograms (ECGs) findings
measured up to approximately 9 months
Number of participants with abnormal changes in clinical laboratory tests
measured up to approximately 9 months
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