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Renal Function in Highly Sensitized Patients 1 Year After Desensitization With Imlifidase Prior to DD Kidney Tx

← catalyst calendar

NCT04935177

Sponsored by Hansa Biopharma AB (industry) · HNSA.ST — their whole pipeline →.

Phase
Phase 3
Status
Completed
Study type
Interventional
Design
Randomized · None · Treatment
Enrollment
64actual
Sites
25
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2021-10-14actualWhen the study began enrolling
Primary completion2025-06-20actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2025-06-20actualThe whole study's end, after follow-up
First posted2021-06-22actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-04-30actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Kidney Transplantation in Highly Sensitized Patients

Interventions

  • Drug: Imlifidase — also filed as IdeS, HMED-IdeS
  • Procedure: PLEX — also filed as Plasma exchange, PE
  • Drug: IVIg — also filed as Intravenous immunoglobulin
  • Drug: Anti-CD20 antibodies — also filed as Rituximab
  • Drug: Eculizumab — also filed as Soliris
  • Other: Remain on wait list

Primary outcome

what the primary-completion date above is the date OF
Mean estimated glomerular filtration rate (eGFR) at 12 months
measured 12 months after randomization

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