A Study of ERAS-007 as Monotherapy or in Combination With ERAS-601 in Patients With Advanced or Metastatic Solid Tumors
← catalyst calendarNCT04866134 · readout in 74 d
Sponsored by Erasca, Inc. (industry) · ERAS — their whole pipeline →.
Phase
Phase 1/2
Status
Active, not recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
200estimated
Sites
5
Country
United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2021-05-07 | actual | When the study began enrolling |
| Primary completion | 2026-11-01 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2027-01-01 | estimated | The whole study's end, after follow-up |
| First posted | 2021-04-29 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-06-22 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Advanced or Metastatic Solid Tumors
Interventions
- Drug: ERAS-007
- Drug: ERAS-601
Primary outcomes
what the primary-completion date above is the date OFEvaluate safety and tolerability of escalating doses of ERAS-007 BID-QW
measured Assessed up to 24 months from time of first dose
Dose Limiting Toxicities (DLT)
measured Study Day 1 up to Day 29
Maximum tolerated dose (MTD)
measured Study Day 1 up to Day 29
Recommended dose (RD)
measured Study Day 1 up to Day 29
Adverse Events
measured Assessed up to 24 months from time of first dose
Plasma concentration (Cmax)
measured Study Day 1 up to Day 29
Time to achieve Cmax (Tmax)
measured Study Day 1 up to Day 29
Area under the curve
measured Study Day 1 up to Day 29
Half-life
measured Study Day 1 up to Day 29
Permalink · ERAS's whole pipeline · Catalyst calendar · Every registered study · What changed