RNS System RESPONSE Study
← catalyst calendarSponsored by NeuroPace (industry) · NPCE — their whole pipeline →.
Phase
Not applicable
Status
Terminated
Study type
Interventional
Design
Na · None · Treatment
Enrollment
9actual
Sites
2
Country
United States
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Why the sponsor stopped it
Inadequate Enrollment
As filed on the registry record, in the sponsor's own words.
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2021-10-27 | actual | When the study began enrolling |
| Primary completion | 2025-05-01 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2025-05-01 | actual | The whole study's end, after follow-up |
| First posted | 2021-04-09 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2025-05-22 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Conditions
- Epilepsy
- Partial Seizure
- Neurostimulator; Complications
- Drug Resistant Epilepsy
- Focal Epilepsy
Intervention
- Device: RNS System
Primary outcomes
what the primary-completion date above is the date OFShort-term chronic serious adverse device effect (SADE) rate
measured 84-days post-implant
Responder rate at 12 months post implant
measured The primary effectiveness endpoint is the percent of subjects with a ≥ 50% reduction in seizures at 12 months post-implant compared to the pre-implant baseline.
Publications
- PMID 32690786 — reports results
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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