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Protonix Treatment of Maintenance of Healing in Pediatric Participants Aged 1-11 Years and 12-17 Years

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NCT04821310

Sponsored by Pfizer (industry) · PFE — their whole pipeline →.

Phase
Phase 2
Status
Terminated
Study type
Interventional
Design
Randomized · Quadruple · Treatment
Enrollment
43actual
Sites
27
Countries
Bosnia and Herzegovina, Georgia, India +6

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Why the sponsor stopped it

Pfizer has made an internal business decision to terminate the B1791094 study. This decision was not due to safety concerns or requests from any regulatory authorities.

As filed on the registry record, in the sponsor's own words.

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2022-01-13actualWhen the study began enrolling
Primary completion2025-12-16actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2025-12-16actualThe whole study's end, after follow-up
First posted2021-03-29actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-06-15actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Esophagitis

Interventions

  • Drug: Full dose Pantoprazole plus matching placebo
  • Drug: Half Dose Pantoprazole plus matching placebo

Primary outcome

what the primary-completion date above is the date OF
Proportion of patients with endoscopically confirmed maintenance of healing of erosive esophagitis at Week 24, considering patients with excessive use of rescue medication as treatment failures
measured Week 24

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