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APG-115 in Combination With PD-1 Inhibitor in Patients With Advanced Liposarcoma or Advanced Solid Tumors

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NCT04785196

Sponsored by Ascentage Pharma Group Inc. (industry) · AAPG — their whole pipeline →. With Suzhou Yasheng Pharmaceutical Co., Ltd..

Phase
Phase 1/2
Status
Recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
95estimated
Sites
3
Country
China

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2021-05-26actualWhen the study began enrolling
Primary completionApr 2026estimatedThe date the last participant is measured for the primary outcome — the readout window
Study completionJan 2027estimatedThe whole study's end, after follow-up
First posted2021-03-05actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2025-02-26actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Liposarcoma
  • Advanced Solid Tumor

Interventions

  • Drug: APG-115
  • Drug: Toripalimab

Primary outcomes

what the primary-completion date above is the date OF
Dose Limiting Toxicity (Phase I)
measured 21 days
Recommended Phase II Dose
measured 21 days
Overall Response Rate (Phase II)
measured up to 12 months

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