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Study of AZD2811 + Durvalumab in ES-SCLC

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NCT04745689 · results posted

Sponsored by AstraZeneca (industry) · AZN — their whole pipeline →.

Phase
Phase 2
Status
Active, not recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
31actual
Sites
12
Countries
Poland, South Korea, Spain +1

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2021-02-23actualWhen the study began enrolling
Primary completion2022-06-18actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2026-12-01estimatedThe whole study's end, after follow-up
First posted2021-02-09actualWhen this record first appeared on the registry
Results posted2025-03-27actualWhen the sponsor posted results to the registry
Record updated2026-07-06actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Condition

  • Small-Cell Lung Cancer

Interventions

  • Drug: Durvalumab — also filed as Imfinzi
  • Drug: AZD2811
  • Drug: Carboplatin
  • Drug: Cisplatin
  • Drug: Etoposide

Primary outcome

what the primary-completion date above is the date OF
Maintenance Participants Alive and Progression Free (APF12) Per RECIST 1.1 [Efficacy]
measured Up to 12 months

Posted documents

hosted by the registry — we link, never re-serve
Study Protocolposted 2022-04-21 · 1.5 MB · Prot_000.pdf
Statistical Analysis Planposted 2022-05-05 · 833 KB · SAP_001.pdf

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