MagnetisMM-3: Study Of Elranatamab (PF-06863135) Monotherapy in Participants With Multiple Myeloma Who Are Refractory to at Least One PI, One IMiD and One Anti-CD38 mAb
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Phase
Phase 2
Status
Active, not recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
187actual
Sites
40
Countries
Australia, Canada, France +5
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2021-02-02 | actual | When the study began enrolling |
| Primary completion | 2022-06-17 | actual | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2026-12-31 | estimated | The whole study's end, after follow-up |
| First posted | 2020-12-02 | actual | When this record first appeared on the registry |
| Results posted | 2023-10-25 | actual | When the sponsor posted results to the registry |
| Record updated | 2026-05-19 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Multiple Myeloma
Intervention
- Drug: Elranatamab (PF-06863135)
Primary outcome
what the primary-completion date above is the date OFObjective Response Rate (ORR) by Blinded Independent Central Review (BICR) as Per International Myeloma Working Group (IMWG) Criteria
measured From date of first dose until confirmed disease progression, death, start of new anticancer therapy, whichever occurred first (up to approximately 16 months)
Posted documents
hosted by the registry — we link, never re-serveStudy Protocolposted 2023-03-22 · 1.1 MB · Prot_000.pdf
Statistical Analysis Planposted 2022-10-26 · 2.8 MB · SAP_001.pdf
Publications
- PMID 42287565 — linked by the registry
- PMID 42021581 — linked by the registry
- PMID 41968022 — linked by the registry
- PMID 40830740 — linked by the registry
- PMID 40826257 — linked by the registry
- PMID 40495704 — linked by the registry
- PMID 40000533 — linked by the registry
- PMID 38794892 — linked by the registry
- PMID 38078866 — linked by the registry
- PMID 37582952 — linked by the registry
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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