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FT819 in Subjects With B-cell Malignancies

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NCT04629729

Sponsored by Fate Therapeutics (industry) · FATE — their whole pipeline →.

Phase
Phase 1
Status
Active, not recruiting
Study type
Interventional
Design
Non randomized · None · Treatment
Enrollment
54actual
Sites
18
Country
United States

Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →

Source: ClinicalTrials.gov, retrieved 2026-08-19

Dates

each axis at the precision it was filed, with the registry's own basis
DateFiledBasisWhat it is
Start2021-07-12actualWhen the study began enrolling
Primary completion2025-06-18actualThe date the last participant is measured for the primary outcome — the readout window
Study completion2039-09-30estimatedThe whole study's end, after follow-up
First posted2020-11-16actualWhen this record first appeared on the registry
Results postedWhen the sponsor posted results to the registry
Record updated2026-03-19actualThe sponsor's own last edit to this record — every projection above is as current as this date

What it studies

Conditions

  • Lymphoma, B-Cell
  • Chronic Lymphocytic Leukemia
  • Precursor B-Cell Acute Lymphoblastic Leukemia

Interventions

  • Drug: FT819
  • Drug: Cyclophosphamide
  • Drug: Fludarabine — also filed as Fludara
  • Drug: IL-2 — also filed as Interleukin-2
  • Drug: Bendamustine — also filed as Bendeka, Treanda

Primary outcomes

what the primary-completion date above is the date OF
Incidence and nature of dose-limiting toxicities within each dose level cohort
measured Up to Day 29
Incidence, nature, and severity of adverse events (AEs) of FT819 as monotherapy and in combination with IL-2 in r/r B-cell lymphoma, r/r chronic lymphocytic leukemia, and r/r precursor B-cell acute lymphoblastic leukemia
measured Up to 15 years

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