Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis
← catalyst calendarNCT04624230 · readout in 210 d
Sponsored by Pfizer (industry) · PFE — their whole pipeline →.
Phase
Phase 3
Status
Active, not recruiting
Study type
Interventional
Design
Na · None · Treatment
Enrollment
118actual
Sites
69
Countries
Australia, Belgium, Canada +13
Every value on this page is a field the sponsor filed with ClinicalTrials.gov, reproduced. Dates are their own estimates, revised as a study runs, unless the registry marks them actual. sources →
Source: ClinicalTrials.gov, retrieved 2026-08-19
Dates
each axis at the precision it was filed, with the registry's own basis| Date | Filed | Basis | What it is |
|---|---|---|---|
| Start | 2021-08-12 | actual | When the study began enrolling |
| Primary completion | 2027-03-17 | estimated | The date the last participant is measured for the primary outcome — the readout window |
| Study completion | 2029-06-06 | estimated | The whole study's end, after follow-up |
| First posted | 2020-11-10 | actual | When this record first appeared on the registry |
| Results posted | — | When the sponsor posted results to the registry | |
| Record updated | 2026-08-03 | actual | The sponsor's own last edit to this record — every projection above is as current as this date |
What it studies
Condition
- Ulcerative Colitis
Intervention
- Drug: tofacitinib
Primary outcome
what the primary-completion date above is the date OFRemission by central read Mayo score following 44 weeks in the maintenance phase.
measured Outcome measured at the end of the 44 weeks of the maintenance phase.
Publications
- PMID 28417994 — reports results
- PMID 31504429 — reports results
- PMID 32079889 — reports results
- PMID 17681163 — reports results
- PMID 12394384 — reports results
- PMID 27159210 — reports results
- PMID 11237120 — reports results
Linked on the registry record. A “linked by the registry” entry is NLM's own automated PubMed match, not a claim by the sponsor that the paper reports this study.
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